Special Issues

Special Issue Title: Ischemic stroke: new diagnostic tools and therapeutic strategies in the era of recanalization

·  Print Special Issue Flyer

·  Deadline for manuscript submissions: 1 November 2021

Special Issue Editor

Guest Editor

  Dr. Juan B. Salom

  1. Joint Unit for Cerebrovascular Research, La Fe Health Research Institute, Valencia, Spain

  2. Department of Physiology, University of Valencia, Valencia, Spain

Website | E-Mail

Interests: Ischemic stroke, animal models, ischemic brain damage, cell senescence, neuroprotection, new therapies

Dr. Ramón Iglesias-Rey

Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), Clinical University Hospital (CHUS), SERGAS, Travesía da Choupana, Santiago de Compostela, Spain

Website | E-Mail

Interests: Bioimage, ischemic stroke, animal models, magnetic resonance imaging (mri), molecular imaging, nanoparticles, nanomedicine

Special Issue Information

Dear Colleagues,

Stroke remains a global leading cause of death and permanent disability. Ischemic stroke is by far the most common kind of stroke, accounting for more than 85% of all strokes. Large vessel occlusions (LVOs), defined as blockages of the proximal intracranial anterior and posterior circulation, account for more than 40% of ischemic strokes.  Intravenous thrombolysis with rtPA used to be the only reperfusion therapy. However, endovascular therapies including mechanical thrombectomy has revolutionized acute care of LVOs. This opens opportunities for the reevaluation of the entire chain of stroke care delivery, including diagnosis, neuroprotection and neuroreparation in the context of the neurovascular unit.

The present special issue welcomes papers on ischemic stroke, with special focus on, but not limited to, preclinical and clinical studies which results could pave the way for accurate diagnostic as well as effective neuroprotection and neuroreparation. A non-exclusive inspiring list of subjects could be the improvement of recanalization therapies, new thrombolytic agents, and reevaluation of neuroprotective compounds in the light of new standards for a rigorous preclinical testing. Non-drug based approaches, such as ischemic tolerance and hypothermia should also be considered. In this line, nano-drug delivery platforms will be positively assessed. Post-stroke neuroregeneration boosted by stem-cell based interventions is also a promising field. Finally, research works based on molecular imaging for diagnosis, prognosis, and evaluation of ischemic damage are suitable for this issue.

Dr. Juan B. Salom and Dr. Ramón Iglesias-Rey

Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at https://jour.ipublishment.com/imr/access/login by registering and logging into this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Integrative Neuroscience is an international peer-reviewed open access quarterly journal published by IMR Press.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is $1500. We normally offer a discount greater than 30% (APC: $1050) to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.


Ischemic stroke, ischemic brain damage, magnetic resonance imaging (MRI), molecular imaging, neuroprotection; neuroreparation, nanoparticles, nanomedicine

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