#### Special Issues

Special Issue Title: Neurodegeneration and neuroinflammation

·  Deadline for manuscript submissions: 1 March 2021

Special Issue Editor

Guest Editor

 Prof. Jolanta Dorszewska Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland

Interests: Alzheimer’s disease, Parkinson’s disease, epilepsy, genetics, genomics, molecular biology, clinical trials, genetic analysis, neurodegeneration, neurological diseases, neurodegenerative diseases, neurobiology

Special Issue Information

Dear Colleagues,

The causes of central neurodegenerative changes in the course of neurological diseases such as Alzheimer's disease and Parkinson's disease and many others are not fully explained. It is known that these are multifactorial genetic and environmental diseases. While the cause of single gene diseases is better understood, the share of genes in multi-gene diseases is not fully understood. Among the environmental factors that cause neurodegeneration, changes in the immune system are pointed. What is more, in recent years there are more papers suggesting that Alzheimer's disease may have an infectious origin. Bacteria responsible for gum disease, rheumatoid arthritis, and atherosclerosis have been found in the body of deceased people who had Alzheimer's disease.

Recent reports indicate that more than a third of COVID-19 patients have neurological symptoms, including from the central nervous system, even as severe as stroke or impaired consciousness. It has been suggested that an infection has been a risk factor for neurodegenerative diseases. Therefore, increased exposure to infections, especially in people under 60 years of age, may contribute to a greater number of cases of neurodegenerative diseases and their course in the future. Will be after this infection new biomarkers predisposing to the occurrence of old age diseases? Will there be new neuroimaging changes to facilitate early diagnosis of degenerative diseases? Will this knowledge contribute to the development of new, more effective therapies for neurodegenerative diseases?

In this Special Issue, we will try to explain the impact of immune changes associated with infections and their effects on the development of neurodegeneration and the emergence of diseases of old age.

Prof. Jolanta Dorszewska

Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at https://jour.ipublishment.com/imr/access/login by registering and logging into this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the page. Journal of Integrative Neuroscience is an international peer-reviewed open access quarterly journal published by IMR Press.

Please visit thepage before submitting a manuscript. The for publication in this open access journal is $1500. We normally offer a discount greater than 30% (APC:$1050) to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

Keywords

Genetics, inflammation, neurodegenerative diseases

Planned Paper (3 papers)

Title: Antiviral, immunomodulatory and neuroprotective effects of lithium
Author(s): Janusz Rybakowski

Title: Infectious agents and Alzheimer's disease
Author(s): Thomas Piekut, Mikołaj Hurła, Natalia Banaszek, Paulina Szejn, Wojciech Kozubski, Michał Prendecki

Title: Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and neurological disease target in the brain
Author(s): Agata Różycka