In the past and actually, many studies have
been focus in neuronal cells but they have not given enough interest to glial
cells and their development. In the last decade the study of these cells has
increased and their morphology, the changes during development, their role in
neurodegeneration, the damage produced by drugs and in the brain development
are now a great field of study in science. Furthermore, expression of the
receptors on the surface conditioner axonal neuronal direction and cell
adhesion, jogging many roles in brain function. Also, the susceptibility of
different brain regions to the disease that are linked to the overstimulation
of microglia and astrocytes, could be linked to the immune system during aging
as well as development brain. On the other hand, a diminution in glia phagocytosis
has related to many diseases, such as AD, ALS, cancer, developmental disorders,
neurodegeneration, pain related disorders and destruction of the BBB. This
issue will focus in the mechanisms of action of glial cells and their role
during aging and development diseases.
Assistant Prof. Dr. Soraya L. Valles
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Astrocytes, oligodendroglia, microglia, development disease, neurodegenerative disease, cancer